Malte Kaspereit

Prof. Dr. Malte Kaspereit

Professor for Separation Science & Technology

Department of Chemical and Biological Engineering (CBI)
Institute of Separation Science & Technology (TVT)

Room T 3.63
Egerlandstr. 3
91058 Erlangen
Germany

Phone number: +49 9131 85-27638
Fax number: +49 9131 85-27441
Email: malte.kaspereit@fau.de
Website: https://www.asp.forschung.fau.de

Research

Malte Kaspereit is head of the research group Advanced Separation Processes, which is located at the Institute of Separation Science & Technology (Lehrstuhl für Thermische Verfahrenstechnik, TVT). The institute is part of the Department for Chemical and Biological Engineering (CBI) in the Faculty of Engineering (Technische Fakultät) at Friedrich Alexander University Erlangen-Nürnberg (FAU), Germany.

Malte Kaspereit’s research is devoted to the development of efficient processes for current challenging separation problems that occur in productions of bulk and fine chemicals, pharmaceuticals, and biological products. Particular focus is on powerful approaches like preparative chromatography, membrane-based separations, gas adsorption, as well as hybrid and reactive separations. The work is based on a strong experimental and theoretical background. Please check out our research pages for more details.

For his research, Malte Kaspereit received several awards. Among them is the Young lecturer’s award (Hochschullehrer-Nachwuchspreis) of Dechema, and the Award for Technology and Science (Technikwissenschaftlicher Preis) of the Berlin-Brandenburg Academy of Sciences and Humanities (Berlin-Brandenburgische Akademie der Wissenschaften).

Curriculum vitae

Malte Kaspereit studied Process Engineering (Verfahrenstechnik) at the Technical University of Clausthal, Germany. After a six-month research visit at the College of Engineering at Purdue University (W Lafayette/IN, USA) he joined the Max Planck Institute for Dynamics of Complex Technical Systems (MPI) in Magdeburg, Germany. He obtained his PhD “with honors” from Otto von Guericke University in Magdeburg under supervision of Andreas Seidel-Morgenstern. After several years as PostDoc at MPI, he accepted the offered Professorship for Separation Science & Technology at FAU.

Publications

2020

Dienstbier, J., Schmölder, J., Burlacu, R., Liers, F., & Kaspereit, M. (2020). Global optimization of batch and steady-state recycling chromatography based on the equilibrium model. Computers & Chemical Engineering, 135, 106687. https://doi.org/10.1016/j.compchemeng.2019.106687
Haider, B., Dilshad, M.R., Ur Rehman, M.A., Akram, M.S., & Kaspereit, M. (2020). Highly permeable innovative PDMS coated polyethersulfone membranes embedded with activated carbon for gas separation. Journal of Natural Gas Science and Engineering, 81. https://doi.org/10.1016/j.jngse.2020.103406
Haider, B., Dilshad, M.R., Ur Rehman, M.A., Vargas Schmitz, J., & Kaspereit, M. (2020). Highly permeable novel PDMS coated asymmetric polyethersulfone membranes loaded with SAPO-34 zeolite for carbon dioxide separation. Separation and Purification Technology, 248. https://doi.org/10.1016/j.seppur.2020.116899
Jupke, A., Biselli, A., Kaspereit, M., Leipnitz, M., & Schmidt-Traub, H. (2020). Process design and optimization. In Henner Schmit-Traub, Michael Schulte, Andreas Seidel-Morgenstern (Eds.), Preparative Chromatography: Third Edition. (pp. 409-501). John Wiley & Sons, Ltd..
Kaspereit, M., & Schmidt-Traub, H. (2020). Process concepts. In Henner Schmit-Traub, Michael Schulte, Andreas Seidel-Morgenstern (Eds.), Preparative Chromatography: Third Edition. John Wiley & Sons, Ltd..
Schmölder, J., & Kaspereit, M. (2020). A Modular Framework for the Modelling and Optimization of Advanced Chromatographic Processes. Processes, 8. https://doi.org/10.3390/pr8010065

2019

Hartmann, M., Reif, B., Paula, C., Fabisch, F., Hartmann, M., Kaspereit, M., & Schwieger, W. (2019). Synthesis of ZIF-11 – Influence of the synthesis parameters on the phase purity. Microporous and Mesoporous Materials, 275, 102-110. https://doi.org/10.1016/j.micromeso.2018.08.019
Kriesten, M., Vargas Schmitz, J., Siegel, J., Smith, C.E., Kaspereit, M., & Hartmann, M. (2019). Shaping of Flexible Metal-Organic Frameworks: Combining Macroscopic Stability and Framework Flexibility. European Journal of Inorganic Chemistry, 43, 4700-4709. https://doi.org/10.1002/ejic.201901100
Reif, B., Somboonvong, J., Fabisch, F., Kaspereit, M., Hartmann, M., & Schwieger, W. (2019). Solvent-free transformation of spray coated ZnO layers to ZIF-8 membranes. Microporous and Mesoporous Materials, 276, 29-40. https://doi.org/10.1016/j.micromeso.2018.09.024
Reuß, S., Reif, B., Sanwald, D., Schwieger, W., Kaspereit, M., Singh, P.S.,... Alyoubi, A.O. (2019). Sequential Template Decomposition to Adjust the Performance of Imperfect Zeolite BEA Membranes. Chemie Ingenieur Technik, 91(7), 953-960. https://doi.org/10.1002/cite.201800189
Süß, S., Michaud, V., Amsharov, K., Akhmetov, V., Kaspereit, M., Damm, C., & Peukert, W. (2019). Quantitative Evaluation of Fullerene Separation by Liquid Chromatography. Journal of Physical Chemistry C, 123(27), 16747-16756. https://doi.org/10.1021/acs.jpcc.9b03247
Vargas Schmitz, J., Kriesten, M., Hartmann, M., & Kaspereit, M. (2019). Model development for the separation of a strongly adsorbing gas mixture on a semi-pilot scale adsorber. Separation and Purification Technology, 217, 48-61. https://doi.org/10.1016/j.seppur.2019.02.004

2018

Fechtner, M., Kaspereit, M., & Kienle, A. (2018). Efficient simulation of ion exchange chromatography with application to bioseparations. Computer Aided Chemical Engineering, 43, 295-300. https://doi.org/10.1016/B978-0-444-64235-6.50055-3

2017

Hovestadt, M., Vargas Schmitz, J., Weissenberger, T., Reif, F., Kaspereit, M., Schwieger, W., & Hartmann, M. (2017). Scale-up of the Synthesis of Zeolitic Imidazolate Framework ZIF-4. Chemie Ingenieur Technik, 89(10), 1374-1378. https://doi.org/10.1002/cite.201700105

2016

Hartmann, M., Vargas Schmitz, J., Hovestadt, M., Kriesten, M., Hartmann, M., & Kaspereit, M. (2016). On the dynamics of gas adsorption processes for systems governed by different phenomena. In Proceedings of the 22nd International Congress of Chemical and Process Engineering, CHISA 2016 and 19th Conference on Process Integration, Modelling and Optimisation for Energy Saving and Pollution Reduction, PRES 2016 (pp. 451-452). Czech Society of Chemical Engineering.
Kaspereit, M., & Neupert, B. (2016). Using the Hodograph Space for the Simplified Design of Simulated Moving Bed Chromatography. Chemie Ingenieur Technik, 88(11), 1628-1642. https://doi.org/10.1002/cite.201600072
Munoz Garcia, M., Kaspereit, M., & Etzold, B. (2016). Deducing kinetic constants for the hydrodechlorination of 4-chlorophenol using high adsorption capacity catalysts. Chemical Engineering Journal, 285, 228-235. https://doi.org/10.1016/j.cej.2015.10.002

2014

Noack, K., Koch, H., Kiefer, J., Kaspereit, M., & Will, S. (2014). Experimentelle und theoretische Untersuchung optisch aktiver Moleküle zur Online-Analyse der Enantiomertrennung mittels Raman-Spektroskopie. In Proceedings of the ProcessNet-Jahrestagung 2014. Aachen.
Swernath, S., Kaspereit, M., & Kienle, A. (2014). Coupled continuous chromatography and racemization processes for the production of pure enantiomers. Chemical Engineering & Technology, 37(4), 643-651. https://doi.org/10.1002/ceat.201300597

2013

Flockerzi, D., Kaspereit, M., & Kienle, A. (2013). Spectral properties of Bi-Langmuir isotherms. Chemical Engineering Science, 104, 957-959. https://doi.org/10.1016/j.ces.2013.09.045
Kaspereit, M., & Górak, A. (2013). A special issue on hybrid and reactive separations. Chemical Engineering and Processing, 67. https://doi.org/10.1016/j.cep.2013.03.009
Kaspereit, M., Schulte, M., Wekenborg, K., & Wewers, W. (2013). Process Concepts. In Henner Schmidt-Traub, Michael Schulte, Andreas Seidel-Morgenstern (Eds.), Preparative Chromatography. (pp. 273-320). Wiley-VCH.
Kaspereit, M., & Seidel-Morgenstern, A. (2013). Process Concepts in Preparative Chromatography. In Salvatore Fanali, Paul R. Haddad, Colin Poole, Peter Schoenmakers, David K. Lloyd (Eds.), Liquid Chromatography - Fundamentals and Instrumentation. (pp. 427-452). Waltham/MA: Elsevier Inc..
Kiefer, J., & Kaspereit, M. (2013). Determination of the Raman depolarization ratio in optically active samples. Analytical Methods, 5(3), 797-800. https://doi.org/10.1039/c2ay25987g
Nimmig, S., & Kaspereit, M. (2013). Continuous production of single enantiomers at high yields by coupling single column chromatography, racemization, and nanofiltration. Chemical Engineering and Processing, 67, 89-98. https://doi.org/10.1016/j.cep.2012.10.013
Sreedhar, B., Wagler, A., Kaspereit, M., & Seidel-Morgenstern, A. (2013). Optimal cut-times finding strategies for collecting a target component from overloaded elution chromatograms. Computers & Chemical Engineering, 49, 158-169. https://doi.org/10.1016/j.compchemeng.2012.09.009
Swernath, S., Kaspereit, M., & Kienle, A. (2013). Dynamics and control of coupled continuous chromatography and crystallization processes for the production of pure enantiomers. Chemical Engineering & Technology, 36(8), 1417-1429. https://doi.org/10.1002/ceat.201200279

2012

Kaemmerer, H., Horvath, Z., Lee, J.W., Kaspereit, M., Arnell, R., Hedberg, M.,... Seidel-Morgenstern, A. (2012). Separation of racemic bicalutamide by an optimized combination of continuous chromatography and selective crystallization. Organic Process Research & Development, 16(2), 331-342. https://doi.org/10.1021/op200136z
Kaspereit, M., Swernath, S., & Kienle, A. (2012). Evaluation of competing process concepts for the production of pure enantiomers. Organic Process Research & Development, 16(2), 353-363. https://doi.org/10.1021/op200285v
Schmidt-Traub, H., Kaspereit, M., Engell, S., Susanto, A., Epping, A., & Jupke, A. (2012). Model-Based Design, Optimization, and Control. In Henner Schmidt-Traub, Michael Schulte, Andreas Seidel-Morgenstern (Eds.), Preparative Chromatography. (pp. 425-518). Wiley-VCH.
von Langermann, J., Kaspereit, M., Shakeri, M., Lorenz, H., Hedberg, M., Jones, M.J.,... Seidel-Morgenstern, A. (2012). Design of an integrated process of chromatography, crystallization and racemization for the resolution of 2′,6′-pipecoloxylidide (PPX). Organic Process Research & Development, 16(2), 343-352. https://doi.org/10.1021/op200268h

2011

García Palacios, J., Kaspereit, M., & Kienle, A. (2011). Integrated Simulated Moving Bed Processes for Production of Single Enantiomers. Chemical Engineering & Technology, 34(5), 688-698. https://doi.org/10.1002/ceat.201000522
García Palacios, J., Kramer, B., Kienle, A., & Kaspereit, M. (2011). Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers. Journal of Chromatography A, 1218(16), 2232-2239. https://doi.org/10.1016/j.chroma.2011.02.021
Kaspereit, M. (2011). Optimal Synthesis and Design of Advanced Chromatographic Process Concepts. Magdeburg: Otto-von-Guericke Universität.
Kaspereit, M., & Sainio, T. (2011). Simplified design of steady-state recycling chromatography under ideal and nonideal conditions. Chemical Engineering Science, 66(21), 5428-5438. https://doi.org/10.1016/j.ces.2011.07.058
Schuur, B., Haan, A.d., Kaspereit, M., & Leeman, M. (2011). Downstream Processing and Product Recovery: Chiral Separations. In Moo-Young M (Eds.), Comprehensive Biotechnology (Second Edition). (pp. 737-751). Elsevier.
Siitonen, J., Sainio, T., & Kaspereit, M. (2011). Theoretical analysis of steady state recycling chromatography with solvent removal. Separation and Purification Technology, 78(1), 21-32. https://doi.org/10.1016/j.seppur.2011.01.013

2010

Mangold, M., Zhang, F., Kaspereit, M., & Kienle, A. (2010). Nonlinear Dynamics of Membrane Reactors. Weinheim, Germany: Wiley-VCH.

2009

García Palacios, J., Kaspereit, M., & Kienle, A. (2009). Conceptual Design of Integrated Chromatographic Processes for the Production of Single (Stereo-)Isomers. Chemical Engineering & Technology, 32(9), 1392-1402. https://doi.org/10.1002/ceat.200900231
García Palacios, J., Kaspereit, M., Ziomek, G., Antos, D., & Seidel-Morgenstern, A. (2009). Optimization and analysis of possible column arrangements for multicomponent separations by preparative chromatography. Industrial & Engineering Chemistry Research, 48(24), 11148-11157. https://doi.org/10.1021/ie900361m
Kaspereit, M. (2009). Advanced operating concepts for simulated moving bed processes. Boca Raton/FL, USA: Marcel Dekker Inc.
Sainio, T., & Kaspereit, M. (2009). Analysis of steady state recycling chromatography using equilibrium theory. Separation and Purification Technology, 66(1), 9-18. https://doi.org/10.1016/j.seppur.2008.12.005

2008

Forssén, P., Arnell, R., Kaspereit, M., Seidel-Morgenstern, A., & Fornstedt, T. (2008). Effects of a strongly adsorbed additive on process performance in chiral preparative chromatography. Journal of Chromatography A, 1212, 89-97. https://doi.org/10.1016/j.chroma.2008.10.040
Jacobs, T., Kaspereit, M., Zeyer, K.-P., Kienle, A., & Hauptmann, P. (2008). Thermal mass flow sensors for monitoring esterification reactions in residence time micro reactors. In Proceedings of the 10th International Conference on Microreaction Technology, IMRET 2008 - Topical Conference at the 2008 AIChE Spring National Meeting (pp. 113-119). New Orleans, LA: American Institute of Chemical Engineers.
Kaspereit, M., García Palacios, J., Meixús Fernández, T., & Kienle, A. (2008). Systematic design of production processes for enantiomers with integration of chromatography and racemisation reactions.
Kessler, C., Seidel-Morgenstern, A., & Kaspereit, M. (2008). New developments in simulated moving bed chromatography. In Proceedings of the 2008 AIChE Annual Meeting, AIChE 100. Philadelphia, PA, US.
Seidel-Morgenstern, A., Keßler, L.C., & Kaspereit, M. (2008). Neue Entwicklungen auf dem Gebiet der simulierten Gegenstromchromatographie. Chemie Ingenieur Technik, 80(6), 725-740. https://doi.org/10.1002/cite.200800042
Seidel-Morgenstern, A., Keßler, L.C., & Kaspereit, M. (2008). New developments in simulated moving bed chromatography. Chemical Engineering & Technology, 31(6), 826-837. https://doi.org/10.1002/ceat.200800081

2007

Gedicke, K., Kaspereit, M., Beckmann, W., Budde, U., Lorenz, H., & Seidel-Morgenstern, A. (2007). Conceptual design and feasibility study of combining continuous chromatography and crystallization for stereoisomer separations. Chemical Engineering Research & Design, 85, 928-936. https://doi.org/10.1205/cherd06224
Jacobs, T., Gomide, A., Kaspereit, M., Zeyer, K.-P., Kienle, A., & Hauptmann, P. (2007). In-line analysis of chemical reactions in micro reactors using thermal mass flow sensors. In IEEE (Eds.), IEEE Catalog (pp. 571-574). Warsaw, PL.
Kaspereit, M., Seidel-Morgenstern, A., & Kienle, A. (2007). Design of simulated moving bed processes under reduced purity requirements. Journal of Chromatography A, 1162, 2-13. https://doi.org/10.1016/j.chroma.2007.02.063
Kulkarni, A., Zeyer, K.-P., Jacobs, T., Kaspereit, M., & Kienle, A. (2007). Feasibility studies and dynamics of catalytic liquid phase esterification reactions in a micro plant. Chemical Engineering Journal, 135. https://doi.org/10.1016/j.cej.2007.07.024
Sainio, T., Kaspereit, M., Kienle, A., & Seidel-Morgenstern, A. (2007). Thermal effects in reactive liquid chromatography. Chemical Engineering Science, 62, 5674-5681. https://doi.org/10.1016/j.ces.2007.02.033

2006

Kaspereit, M. (2006). Separation of Enantiomers by a Process Combination of Chromatography and Crystallisation. Aachen, Germany: Shaker.

2005

Kaspereit, M., Gedicke, K., Zahn, V., Mahoney, A.W., & Seidel-Morgenstern, A. (2005). Shortcut method for evaluation and design of a hybrid process for enantioseparations. Journal of Chromatography A, 1092(1), 43-54. https://doi.org/10.1016/j.chroma.2005.02.043
Ziomek, G., Kaspereit, M., Jeżowski, J., Seidel-Morgenstern, A., & Antos, D. (2005). Effect of mobile phase composition on the SMB processes efficiency: Stochastic optimization of isocratic and gradient operation. Journal of Chromatography A, 1070, 111-124. https://doi.org/10.1016/j.chroma.2005.02.080

2003

Schramm, H., Kaspereit, M., Kienle, A., & Seidel-Morgenstern, A. (2003). Simulated moving bed process with cyclic modulation of the feed concentration. Journal of Chromatography A, 1006, 77-86. https://doi.org/10.1016/S0021-9673(03)00327-3
Schramm, H., Kaspereit, M., Kienle, A., & Seidel-Morgenstern, A. (2003). Verbesserter Betrieb von Simulated Moving Bed-Prozessen durch zyklische Modulation der Feedkonzentration. Chemie Ingenieur Technik, 75(4), 379-383. https://doi.org/10.1002/cite.200390076
Schramm, H., Kienle, A., Kaspereit, M., & Seidel-Morgenstern, A. (2003). Improved operation of simulated moving bed processes through cyclic modulation of feed flow and feed concentration. Chemical Engineering Science, 58, 5217-5227. https://doi.org/10.1016/j.ces.2003.08.015

2002

Kaspereit, M., Jandera, P., Skavrada, M., & Seidel-Morgenstern, A. (2002). Impact of adsorption isotherm parameters on the performance of enantioseparation using simulated moving bed chromatography. Journal of Chromatography A, 944(1-2), 249-262. https://doi.org/10.1016/S0021-9673(01)01341-3
Kaspereit, M., Lorenz, H., & Seidel-Morgenstern, A. (2002). Coupling of Simulated Moving Bed Technology and Crystallization to Separate Enantiomers. In K. Kaneko (Eds.), Fundamentals of Adsorption 7 (pp. 101-108). Nagasaki, JP.
Schramm, H., Kaspereit, M., Kienle, A., & Seidel-Morgenstern, A. (2002). Improving simulated moving bed processes by cyclic modulation of the feed concentration. Chemical Engineering & Technology, 25(12), 1151-1155. https://doi.org/10.1002/1521-4125(20021210)25:12<1151::AID-CEAT1151>3.0.CO;2-Y